1. Home/
  2. Compounds/
  3. Irinotecan

Irinotecan

Synonyms

SourcesNames Used
CCLE, FIMMIrinotecan
gCSIirinotecan
GRAYCPT-11
PharmacoGx Irinotecan

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
Inchikey: UWKQSNNFCGGAFS-XIFFEERXSA-N
Pubchem: 60838

Annotated Targets

TOP1, TOP1MT

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to Irinotecan


Feature TypeStandardized
Nominal ANOVA
mRNA PRR15 gCSI pan-cancer AAC -0.2 0.002
mRNA SUMF1 CCLE pan-cancer AAC -0.19 0.002
mRNA USP45 CCLE pan-cancer AAC 0.17 0.002
mRNA SLC7A3 CCLE pan-cancer AAC 0.17 0.002
mRNA C3orf70 CCLE pan-cancer AAC 0.23 0.002
mRNA SCN10A gCSI pan-cancer AAC -0.17 0.002
mRNA TMEM59 gCSI pan-cancer AAC -0.17 0.002
mRNA PPIH CCLE pan-cancer AAC 0.17 0.002
mRNA PLCD3 CCLE pan-cancer AAC -0.22 0.002
mRNA TIFA gCSI pan-cancer AAC 0.24 0.002
Download CSV