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GRAY

Acronym

Dataset generated in Dr. Joe Gray's lab at the Oregon Health and Science University

Description

As part of the Stand Up to Cancer Breast Cancer Dream Team, the Gray laboratory profiled over 70 breast cancer cell lines and screened them with 90 experimental or approved drugs.

Resources

Affymetrix SNP 6.0 part 1

Affymetrix SNP 6.0 part 2

Affymetrix Exon 1.0 ST array

Affymetrix HG-U133A array

llumina RNA-seq data

Illumina Methylation27 BeadChip

Reverse Protein Lysate Array

Whole Exome-Seq

Publications

Subtype and pathway specific responses to anticancer compounds in breast cancer. Proceedings of the National Academy of Sciences 2011

Modeling precision treatment of breast cancer, Genome Biology 2013

Data types

Data Type Assay/Platform Raw Processed
Pharmacological CellTiter Glo Yes IC50
mRNA expression Affymetrix HG U133A Yes RMA
Affymetrix GC Exon 1.0 ST Yes log-additive PLM
Agilent Automation RNAseq Yes FPKM
DNA Copy Number Affymetrix SNP 6.0 Yes GISTIC
Methylation Illumina Infinium Human Methylation27 Yes Beta Values
Protein Expression RPPA No MicroVigene expression intensity
Exomeseq Agilent Automation Yes

PharmacoGx

PharmacoSet object for: GRAY