PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SUV39H1	CTRPv2	pan-cancer	AAC	-0.2	2e-07
mRNA	DMTN	CTRPv2	pan-cancer	AAC	0.19	2e-07
mRNA	ZNF530	CCLE	pan-cancer	AAC	0.24	2e-07
mRNA	SEPT3	CTRPv2	pan-cancer	AAC	-0.2	2e-07
mRNA	RAB39A	CTRPv2	pan-cancer	AAC	-0.2	2e-07
mRNA	FLAD1	CTRPv2	pan-cancer	AAC	-0.2	3e-07
mRNA	GFI1B	CTRPv2	pan-cancer	AAC	0.18	3e-07
mRNA	MTOR	CTRPv2	pan-cancer	AAC	-0.19	3e-07
mRNA	MFSD2B	CTRPv2	pan-cancer	AAC	0.18	4e-07
mRNA	APOO	CTRPv2	pan-cancer	AAC	-0.19	4e-07