PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ESRRG	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	NDRG3	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	CENPJ	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	PAQR4	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	ZNF684	CTRPv2	pan-cancer	AAC	-0.1	0.004
mRNA	DDAH2	CCLE	pan-cancer	AAC	0.15	0.004
mRNA	MTPN	CTRPv2	pan-cancer	AAC	-0.12	0.004
mRNA	ACOX1	CCLE	pan-cancer	AAC	0.15	0.004
mRNA	IVL	CCLE	pan-cancer	AAC	0.14	0.004
mRNA	CDYL2	CCLE	pan-cancer	AAC	-0.14	0.004