PharmacoDB

Sources

Names Used

AZD0530

Saracatinib

saracatinib

PharmacoGx

AZD0530

Database	Identifier
Smiles:	CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Inchikey:	OUKYUETWWIPKQR-UHFFFAOYSA-N
Pubchem:	10302451

Database

Identifier

Smiles:

CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6

Inchikey:

OUKYUETWWIPKQR-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to AZD0530

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KLF1	CTRPv2	pan-cancer	AAC	0.2	3e-08
mRNA	SLC25A37	CTRPv2	pan-cancer	AAC	0.2	4e-08
mRNA	SAP30	CTRPv2	pan-cancer	AAC	-0.23	4e-08
mRNA	FAM117A	CTRPv2	pan-cancer	AAC	0.23	5e-08
mRNA	STON2	CTRPv2	pan-cancer	AAC	0.2	6e-08
mRNA	MCU	CCLE	pan-cancer	AAC	0.28	6e-08
mRNA	BMP2K	CTRPv2	pan-cancer	AAC	0.21	8e-08
mRNA	RBM10	CTRPv2	pan-cancer	AAC	-0.21	8e-08
mRNA	RIPPLY2	CTRPv2	pan-cancer	AAC	-0.22	8e-08
mRNA	NABP2	CTRPv2	pan-cancer	AAC	-0.19	9e-08