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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA FAM117B CTRPv2 pan-cancer AAC 0.24 1e-14
mRNA C1QBP gCSI pan-cancer AAC 0.37 2e-14
mRNA HNRNPA1 CTRPv2 pan-cancer AAC 0.25 5e-13
mRNA SENP3-EIF4A1 gCSI pan-cancer AAC 0.35 5e-13
mRNA EIF4A1 gCSI pan-cancer AAC 0.35 7e-13
mRNA RTFDC1 CTRPv2 pan-cancer AAC -0.22 1e-12
mRNA NUP133 CTRPv2 pan-cancer AAC 0.21 2e-12
mRNA SAFB CTRPv2 pan-cancer AAC 0.24 4e-12
mRNA DOT1L CTRPv2 pan-cancer AAC 0.25 7e-12
mRNA H3F3A CTRPv2 pan-cancer AAC 0.22 8e-12
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