1. Home/
  2. Compounds/
  3. lapatinib

lapatinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastLapatinib
gCSI, CTRPv2lapatinib
PharmacoGx lapatinib

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
Inchikey: BCFGMOOMADDAQU-UHFFFAOYSA-N
Pubchem: 208908

Annotated Targets

ERBB2, EGFR

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to lapatinib


Feature TypeStandardized
Nominal ANOVA
mRNA BPIFB1 GDSC1000 pan-cancer AAC 0.18 0.0002
mRNA EVI2A CCLE pan-cancer AAC -0.2 0.0002
mRNA HIVEP1 UHNBreast pan-cancer AAC 0.85 0.0002
mRNA AL591806.1 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA S100A16 UHNBreast pan-cancer AAC 0.85 0.0002
mRNA NRSN2 gCSI pan-cancer AAC -0.23 0.0002
mRNA STAP2 CCLE pan-cancer AAC 0.19 0.0002
mRNA RGS4 CCLE pan-cancer AAC -0.18 0.0002
mRNA USP1 GDSC1000 pan-cancer AAC -0.18 0.0002
mRNA SRM gCSI pan-cancer AAC -0.2 0.0002
Download CSV