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paclitaxel

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastPaclitaxel
gCSI, CTRPv2paclitaxel
PharmacoGx paclitaxel

External IDs

DatabaseIdentifier
Smiles: CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)[C@@H]4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7
Inchikey: RCINICONZNJXQF-MZXODVADSA-N
Pubchem: 36314

Annotated Targets

BCL2, MAP2, MAP4, MAPT, NR1I2, TLR4, TUBB, TUBB1

FDA Approval Status

Approved
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Top molecular features associated with response to paclitaxel


Feature TypeStandardized
Nominal ANOVA
mRNA SRSF3 CTRPv2 pan-cancer AAC 0.19 5e-08
mRNA PHF5A CCLE pan-cancer AAC 0.24 5e-08
mRNA THAP11 CCLE pan-cancer AAC 0.24 5e-08
mRNA ADGRG1 gCSI pan-cancer AAC -0.35 6e-08
mRNA ELOVL1 CTRPv2 pan-cancer AAC -0.2 6e-08
mRNA GRAMD3 CTRPv2 pan-cancer AAC -0.19 6e-08
mRNA DAZAP1 CTRPv2 pan-cancer AAC 0.22 6e-08
mRNA MYOF CTRPv2 pan-cancer AAC -0.21 6e-08
mRNA NUP160 gCSI pan-cancer AAC 0.28 6e-08
mRNA TFAP4 CTRPv2 pan-cancer AAC 0.2 6e-08
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