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AZD6244

Synonyms

SourcesNames Used
CCLE, GRAY, UHNBreastAZD6244
GDSC1000, CTRPv2selumetinib
FIMMSelumetinib
PharmacoGx AZD6244

External IDs

DatabaseIdentifier
Smiles: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
Inchikey: CYOHGALHFOKKQC-UHFFFAOYSA-N
Pubchem: 10127622

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD6244


Feature TypeStandardized
Nominal ANOVA
mRNA CXCR2 CCLE pan-cancer AAC 0.27 2e-10
mRNA DUSP6 CCLE pan-cancer AAC 0.29 2e-10
mRNA HSD17B11 CTRPv2 pan-cancer AAC 0.23 3e-10
mRNA HSD17B6 CCLE pan-cancer AAC -0.29 3e-10
mRNA GJB1 CCLE pan-cancer AAC 0.3 4e-10
mRNA KCNN4 CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA BACH2 CCLE pan-cancer AAC -0.3 5e-10
mRNA SH3TC2 CTRPv2 pan-cancer AAC 0.26 5e-10
mRNA SPRY4 CTRPv2 pan-cancer AAC 0.24 5e-10
mRNA ETV4 CCLE pan-cancer AAC 0.3 5e-10
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