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AZD6244

Synonyms

SourcesNames Used
CCLE, GRAY, UHNBreastAZD6244
GDSC1000, CTRPv2selumetinib
FIMMSelumetinib
PharmacoGx AZD6244

External IDs

DatabaseIdentifier
Smiles: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
Inchikey: CYOHGALHFOKKQC-UHFFFAOYSA-N
Pubchem: 10127622

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD6244


Feature TypeStandardized
Nominal ANOVA
mRNA TUBAL3 CCLE pan-cancer AAC 0.15 0.0004
mRNA ERCC6L CTRPv2 pan-cancer AAC -0.12 0.0004
mRNA ZNF2 CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA GPR137B CTRPv2 pan-cancer AAC 0.14 0.0004
mRNA PAPD5 CTRPv2 pan-cancer AAC -0.13 0.0004
mRNA P2RX1 CCLE pan-cancer AAC 0.18 0.0004
mRNA RACGAP1 CTRPv2 pan-cancer AAC -0.12 0.0004
mRNA P2RY2 CCLE pan-cancer AAC 0.17 0.0004
mRNA DSTYK CCLE pan-cancer AAC 0.17 0.0004
mRNA ZFPM1 CTRPv2 pan-cancer AAC 0.13 0.0004
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