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AZD6244

Synonyms

SourcesNames Used
CCLE, GRAY, UHNBreastAZD6244
GDSC1000, CTRPv2selumetinib
FIMMSelumetinib
PharmacoGx AZD6244

External IDs

DatabaseIdentifier
Smiles: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
Inchikey: CYOHGALHFOKKQC-UHFFFAOYSA-N
Pubchem: 10127622

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD6244


Feature TypeStandardized
Nominal ANOVA
mRNA NRROS CTRPv2 pan-cancer AAC 0.28 7e-10
mRNA PARP4 CTRPv2 pan-cancer AAC 0.23 7e-10
mRNA CSF3R CCLE pan-cancer AAC 0.26 8e-10
mRNA ABHD14A-ACY1 CTRPv2 pan-cancer AAC 0.23 9e-10
mRNA TMEM105 CTRPv2 pan-cancer AAC 0.22 1e-09
mRNA ITGA6 CTRPv2 pan-cancer AAC 0.26 1e-09
mRNA GPX1 CTRPv2 pan-cancer AAC 0.21 1e-09
mRNA SENP1 CTRPv2 pan-cancer AAC -0.23 1e-09
mRNA BCL7A CTRPv2 pan-cancer AAC -0.24 2e-09
mRNA TMC6 CTRPv2 pan-cancer AAC 0.24 2e-09
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