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Vorinostat

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMVorinostat
gCSI, CTRPv2vorinostat
PharmacoGx Vorinostat

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Inchikey: WAEXFXRVDQXREF-UHFFFAOYSA-N
Pubchem: 5311

Annotated Targets

HDAC6, HDAC1, HDAC2, HDAC3, HDAC10, HDAC11, HDAC5, HDAC8, HDAC9

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Vorinostat


Feature TypeStandardized
Nominal ANOVA
mRNA CBX2 GDSC1000 pan-cancer AAC 0.23 8e-13
mRNA MYOF CTRPv2 pan-cancer AAC -0.27 1e-12
mRNA HNRNPA1L2 GDSC1000 pan-cancer AAC 0.24 1e-12
mRNA MYO1C GDSC1000 pan-cancer AAC -0.28 2e-12
mRNA CBX2 CTRPv2 pan-cancer AAC 0.26 2e-12
mRNA MURC GDSC1000 pan-cancer AAC 0.23 4e-12
mRNA TET1 GDSC1000 pan-cancer AAC 0.23 4e-12
mRNA BCL9L GDSC1000 pan-cancer AAC -0.27 5e-12
mRNA MVP GDSC1000 pan-cancer AAC -0.23 6e-12
mRNA SRSF7 GDSC1000 pan-cancer AAC 0.23 6e-12
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