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Vorinostat

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMVorinostat
gCSI, CTRPv2vorinostat
PharmacoGx Vorinostat

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Inchikey: WAEXFXRVDQXREF-UHFFFAOYSA-N
Pubchem: 5311

Annotated Targets

HDAC6, HDAC1, HDAC2, HDAC3, HDAC10, HDAC11, HDAC5, HDAC8, HDAC9

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Vorinostat


Feature TypeStandardized
Nominal ANOVA
mRNA LMNA GDSC1000 pan-cancer AAC -0.28 7e-12
mRNA SP100 GDSC1000 pan-cancer AAC -0.23 7e-12
mRNA PEA15 GDSC1000 pan-cancer AAC -0.24 8e-12
mRNA TNFRSF12A GDSC1000 pan-cancer AAC -0.31 1e-11
mRNA DRAP1 CTRPv2 pan-cancer AAC -0.23 2e-11
mRNA ILF3 GDSC1000 pan-cancer AAC 0.22 2e-11
mRNA YAP1 GDSC1000 pan-cancer AAC -0.31 2e-11
mRNA DNMT3A CTRPv2 pan-cancer AAC 0.24 2e-11
mRNA MARCKSL1 CTRPv2 pan-cancer AAC 0.22 2e-11
mRNA FAM114A1 GDSC1000 pan-cancer AAC -0.26 2e-11
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