PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MCF2L	GDSC1000	pan-cancer	AAC	-0.22	2e-11
mRNA	STK17A	GDSC1000	pan-cancer	AAC	0.23	2e-11
mRNA	KLHL5	GDSC1000	pan-cancer	AAC	0.22	2e-11
mRNA	ITPRIP	GDSC1000	pan-cancer	AAC	0.22	2e-11
mRNA	SERPINE1	GDSC1000	pan-cancer	AAC	0.25	3e-11
mRNA	UCP2	GDSC1000	pan-cancer	AAC	-0.24	3e-11
mRNA	CYR61	GDSC1000	pan-cancer	AAC	0.3	3e-11
mRNA	NOL4	GDSC1000	pan-cancer	AAC	-0.22	3e-11
mRNA	HECTD4	GDSC1000	pan-cancer	AAC	-0.22	4e-11
mRNA	ASCL1	GDSC1000	pan-cancer	AAC	-0.23	4e-11