PharmacoDB

Sources

Names Used

Docetaxel

docetaxel

PharmacoGx

Docetaxel

Database	Identifier
Smiles:	CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O
Inchikey:	ZDZOTLJHXYCWBA-VCVYQWHSSA-N
Pubchem:	148124

Database

Identifier

Smiles:

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Inchikey:

ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Pubchem:

Top molecular features associated with response to Docetaxel

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GADD45G	GDSC1000	pan-cancer	AAC	-0.23	2e-12
mRNA	INSM1	GDSC1000	pan-cancer	AAC	-0.24	3e-12
mRNA	SEZ6	GDSC1000	pan-cancer	AAC	-0.22	5e-12
mRNA	IGF2BP2	GDSC1000	pan-cancer	AAC	0.26	5e-12
mRNA	IGFBP6	GDSC1000	pan-cancer	AAC	0.26	7e-12
mRNA	YAP1	GDSC1000	pan-cancer	AAC	0.32	8e-12
mRNA	SBK1	GDSC1000	pan-cancer	AAC	-0.24	8e-12
mRNA	RRAS	GDSC1000	pan-cancer	AAC	0.27	1e-11
mRNA	TFF3	GDSC1000	pan-cancer	AAC	-0.23	2e-11
mRNA	COL7A1	GDSC1000	pan-cancer	AAC	0.25	2e-11