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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA SOX15 gCSI pan-cancer AAC 0.24 0.0003
mRNA EREG gCSI pan-cancer AAC 0.22 0.0003
mRNA AP1M2 gCSI pan-cancer AAC 0.26 0.0003
mRNA HCAR1 gCSI pan-cancer AAC 0.22 0.0003
mRNA EPN3 gCSI pan-cancer AAC 0.24 0.0003
mRNA UAP1L1 gCSI pan-cancer AAC -0.21 0.0003
mRNA GBP4 gCSI pan-cancer AAC 0.2 0.0003
mRNA SCMH1 gCSI pan-cancer AAC -0.2 0.0003
mRNA CDC34 gCSI pan-cancer AAC -0.21 0.0003
mRNA ALOXE3 gCSI pan-cancer AAC 0.22 0.0003
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