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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM30B CCLE pan-cancer AAC 0.37 5e-12
mRNA MPZL2 CCLE pan-cancer AAC 0.37 6e-12
mRNA P2RY2 CCLE pan-cancer AAC 0.34 6e-12
mRNA CDH1 CCLE pan-cancer AAC 0.38 7e-12
mRNA RAB25 CCLE pan-cancer AAC 0.38 1e-11
mRNA TACSTD2 CCLE pan-cancer AAC 0.39 1e-11
mRNA KIAA1522 CCLE pan-cancer AAC 0.42 1e-11
mRNA S100A14 CCLE pan-cancer AAC 0.36 2e-11
mRNA SH3YL1 CCLE pan-cancer AAC 0.32 5e-11
mRNA KLC3 CCLE pan-cancer AAC 0.33 5e-11
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