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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA AP3D1 CTRPv2 pan-cancer AAC -0.12 0.0003
mRNA KRT6C GDSC1000 pan-cancer AAC 0.17 0.0003
mRNA DZIP1 CCLE pan-cancer AAC -0.19 0.0003
mRNA ZC3H12A gCSI pan-cancer AAC 0.21 0.0003
mRNA TMEM184A CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA TUBA1A CTRPv2 pan-cancer AAC -0.14 0.0003
mRNA PBXIP1 FIMM pan-cancer AAC 0.53 0.0003
mRNA RBM8A CTRPv2 pan-cancer AAC -0.12 0.0003
mRNA DUSP1 FIMM pan-cancer AAC -0.84 0.0003
mRNA FBXO43 CTRPv2 pan-cancer AAC -0.13 0.0003
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