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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
Dataset Select
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA BLMH CTRPv2 pan-cancer AAC -0.14 0.0003
mRNA TUBA1A GDSC1000 pan-cancer AAC -0.2 0.0003
mRNA EREG gCSI pan-cancer AAC 0.22 0.0003
mRNA SOX15 gCSI pan-cancer AAC 0.24 0.0003
mRNA AQP12B gCSI pan-cancer AAC -0.21 0.0003
mRNA TSPAN2 CCLE pan-cancer AAC 0.17 0.0003
mRNA MSANTD3-TMEFF1 CTRPv2 pan-cancer AAC -0.15 0.0003
mRNA ANXA2 gCSI pan-cancer AAC 0.26 0.0003
mRNA IPO5 GDSC1000 pan-cancer AAC -0.18 0.0003
mRNA SLC39A11 CCLE pan-cancer AAC 0.17 0.0003
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