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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA GABRR2 CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA INPP4B CCLE pan-cancer AAC 0.19 0.0002
mRNA DSG2 CCLE pan-cancer AAC 0.21 0.0002
mRNA SV2B CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA SLC29A3 CCLE pan-cancer AAC 0.19 0.0002
mRNA ZNF322 CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA MYL6B CCLE pan-cancer AAC -0.18 0.0002
mRNA TBC1D2 GDSC1000 pan-cancer AAC 0.23 0.0002
mRNA PGBD1 CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA TMEM159 CTRPv2 pan-cancer AAC 0.14 0.0002
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