1. Home/
  2. Compounds/
  3. Erlotinib

Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA RBSN CTRPv2 pan-cancer AAC -0.13 0.0003
mRNA HLTF CTRPv2 pan-cancer AAC -0.13 0.0003
mRNA N4BP1 CCLE pan-cancer AAC 0.17 0.0003
mRNA C5orf24 CTRPv2 pan-cancer AAC -0.13 0.0003
mRNA MMP7 GDSC1000 pan-cancer AAC 0.17 0.0003
mRNA MANBA CTRPv2 pan-cancer AAC 0.12 0.0003
mRNA KRT6A GDSC1000 pan-cancer AAC 0.21 0.0003
mRNA MBOAT1 CTRPv2 pan-cancer AAC 0.13 0.0003
mRNA AP1M2 gCSI pan-cancer AAC 0.26 0.0003
mRNA MTUS1 CCLE pan-cancer AAC 0.17 0.0003
Download CSV