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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA FSD1L CCLE pan-cancer AAC -0.16 0.0003
mRNA AC002310.13 CTRPv2 pan-cancer AAC -0.13 0.0003
mRNA ENO2 CTRPv2 pan-cancer AAC -0.13 0.0003
mRNA AC015688.3 CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA TUBA4A CCLE pan-cancer AAC 0.18 0.0003
mRNA FGFR3 CCLE pan-cancer AAC 0.17 0.0003
mRNA RAB20 CCLE pan-cancer AAC 0.18 0.0003
mRNA PMM1 gCSI pan-cancer AAC -0.21 0.0004
mRNA TCEB2 CCLE pan-cancer AAC -0.16 0.0004
mRNA CNTNAP1 CTRPv2 pan-cancer AAC -0.13 0.0004
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