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Erlotinib

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY, FIMM, UHNBreastErlotinib
gCSI, CTRPv2erlotinib
PharmacoGx Erlotinib

External IDs

DatabaseIdentifier
Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
Inchikey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Pubchem: 176871

Annotated Targets

EGFR, NR1I2, ERBB2

FDA Approval Status

Approved
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Top molecular features associated with response to Erlotinib


Feature TypeStandardized
Nominal ANOVA
mRNA STX2 CCLE pan-cancer AAC -0.36 9e-13
mRNA ELF3 CCLE pan-cancer AAC 0.39 1e-12
mRNA ITGB6 CCLE pan-cancer AAC 0.36 1e-12
mRNA GJB3 gCSI pan-cancer AAC 0.49 2e-12
mRNA TMPRSS11E CCLE pan-cancer AAC 0.32 2e-12
mRNA EGFR CCLE pan-cancer AAC 0.42 2e-12
mRNA KLF5 CCLE pan-cancer AAC 0.42 3e-12
mRNA IRF6 CCLE pan-cancer AAC 0.39 3e-12
mRNA FAM216A CCLE pan-cancer AAC -0.33 5e-12
mRNA EPN3 CCLE pan-cancer AAC 0.37 5e-12
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