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FR-180204

FR-180204

Synonyms

Sources	Names Used
GDSC1000	FR-180204
PharmacoGx	FR-180204

External IDs

Database	Identifier
Smiles:	Nc1[nH]nc2nnc(cc12)-c1c(nn2ccccc12)-c1ccccc1
Pubchem:	11493598

Annotated Targets

MAPK1, MAPK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FR-180204

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RNF130	GDSC1000	pan-cancer	AAC	0.19	6e-08
mRNA	PRAM1	GDSC1000	pan-cancer	AAC	0.19	9e-08
mRNA	LYZ	GDSC1000	pan-cancer	AAC	0.19	1e-07
mRNA	CD86	GDSC1000	pan-cancer	AAC	-0.21	1e-07
mRNA	SPNS3	GDSC1000	pan-cancer	AAC	0.2	1e-07
mRNA	KCNE5	GDSC1000	pan-cancer	AAC	0.18	1e-07
mRNA	CD48	GDSC1000	pan-cancer	AAC	-0.26	2e-07
mRNA	NCKAP1L	GDSC1000	pan-cancer	AAC	0.29	2e-07
mRNA	CCR2	GDSC1000	pan-cancer	AAC	0.18	2e-07
mRNA	GCSAM	GDSC1000	pan-cancer	AAC	-0.21	2e-07

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