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FR-180204

FR-180204

Synonyms

Sources	Names Used
GDSC1000	FR-180204
PharmacoGx	FR-180204

External IDs

Database	Identifier
Smiles:	Nc1[nH]nc2nnc(cc12)-c1c(nn2ccccc12)-c1ccccc1
Pubchem:	11493598

Annotated Targets

MAPK1, MAPK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FR-180204

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	OR5K2	GDSC1000	pan-cancer	AAC	-0.069	0.04
mRNA	RAG1	GDSC1000	pan-cancer	AAC	0.072	0.04
mRNA	HGSNAT	GDSC1000	pan-cancer	AAC	0.07	0.04
mRNA	HELT	GDSC1000	pan-cancer	AAC	-0.069	0.04
mRNA	SERPINI1	GDSC1000	pan-cancer	AAC	-0.071	0.04
mRNA	UNC13D	GDSC1000	pan-cancer	AAC	0.077	0.04
mRNA	MGA	GDSC1000	pan-cancer	AAC	0.076	0.04
mRNA	DDX43	GDSC1000	pan-cancer	AAC	-0.071	0.04
mRNA	DHX38	GDSC1000	pan-cancer	AAC	-0.07	0.04
mRNA	MDN1	GDSC1000	pan-cancer	AAC	0.079	0.04

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