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FR-180204

FR-180204

Synonyms

Sources	Names Used
GDSC1000	FR-180204
PharmacoGx	FR-180204

External IDs

Database	Identifier
Smiles:	Nc1[nH]nc2nnc(cc12)-c1c(nn2ccccc12)-c1ccccc1
Pubchem:	11493598

Annotated Targets

MAPK1, MAPK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FR-180204

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRSS57	GDSC1000	pan-cancer	AAC	0.31	4e-18
mRNA	LAIR1	GDSC1000	pan-cancer	AAC	0.35	6e-15
mRNA	MLC1	GDSC1000	pan-cancer	AAC	0.27	1e-13
mRNA	MS4A3	GDSC1000	pan-cancer	AAC	0.23	1e-11
mRNA	LST1	GDSC1000	pan-cancer	AAC	0.28	1e-11
mRNA	RETN	GDSC1000	pan-cancer	AAC	0.23	2e-11
mRNA	PRTN3	GDSC1000	pan-cancer	AAC	0.22	6e-11
mRNA	MS4A6A	GDSC1000	pan-cancer	AAC	0.21	4e-10
mRNA	CLEC11A	GDSC1000	pan-cancer	AAC	0.23	5e-10
mRNA	RASGRP2	GDSC1000	pan-cancer	AAC	0.29	7e-10

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