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FR-180204

FR-180204

Synonyms

Sources	Names Used
GDSC1000	FR-180204
PharmacoGx	FR-180204

External IDs

Database	Identifier
Smiles:	Nc1[nH]nc2nnc(cc12)-c1c(nn2ccccc12)-c1ccccc1
Pubchem:	11493598

Annotated Targets

MAPK1, MAPK3

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FR-180204

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RAB37	GDSC1000	pan-cancer	AAC	0.22	1e-08
mRNA	GNAQ	GDSC1000	pan-cancer	AAC	0.21	1e-08
mRNA	CD33	GDSC1000	pan-cancer	AAC	0.2	1e-08
mRNA	NXF3	GDSC1000	pan-cancer	AAC	0.2	2e-08
mRNA	MS4A4A	GDSC1000	pan-cancer	AAC	0.19	2e-08
mRNA	ELANE	GDSC1000	pan-cancer	AAC	0.19	3e-08
mRNA	MYB	GDSC1000	pan-cancer	AAC	0.28	3e-08
mRNA	GAB2	GDSC1000	pan-cancer	AAC	0.2	4e-08
mRNA	LPAR4	GDSC1000	pan-cancer	AAC	0.19	5e-08
mRNA	NFKB2	GDSC1000	pan-cancer	AAC	-0.19	5e-08

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