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TKI258

TKI258

Synonyms

Sources	Names Used
CCLE	TKI258
PharmacoGx	TKI258

External IDs

Database	Identifier
Smiles:	CN1CCN(CC1)C2=CC3=C(C=C2)NC(=C4C(=C5C(=NC4=O)C=CC=C5F)N)N3
Inchikey:	KCOYQXZDFIIGCY-ZZEZOPTASA-N
Pubchem:	9886808

FDA Approval Status

Not Approved

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Top molecular features associated with response to TKI258

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FBXO7	CCLE	pan-cancer	AAC	0.13	0.02
mRNA	CNKSR1	CCLE	pan-cancer	AAC	-0.14	0.02
mRNA	SNTG1	CCLE	pan-cancer	AAC	-0.11	0.02
mRNA	CPEB4	CCLE	pan-cancer	AAC	-0.11	0.02
mRNA	DHX15	CCLE	pan-cancer	AAC	0.11	0.02
mRNA	GPATCH3	CCLE	pan-cancer	AAC	0.11	0.02
mRNA	ZNF165	CCLE	pan-cancer	AAC	-0.14	0.02
mRNA	SELPLG	CCLE	pan-cancer	AAC	0.14	0.02
mRNA	HNRNPUL1	CCLE	pan-cancer	AAC	0.11	0.02
mRNA	SF3A2	CCLE	pan-cancer	AAC	0.11	0.02

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