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TKI258

TKI258

Synonyms

Sources	Names Used
CCLE	TKI258
PharmacoGx	TKI258

External IDs

Database	Identifier
Smiles:	CN1CCN(CC1)C2=CC3=C(C=C2)NC(=C4C(=C5C(=NC4=O)C=CC=C5F)N)N3
Inchikey:	KCOYQXZDFIIGCY-ZZEZOPTASA-N
Pubchem:	9886808

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TKI258

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SERPINI2	CCLE	pan-cancer	AAC	0.26	1e-08
mRNA	GAPT	CCLE	pan-cancer	AAC	0.29	2e-08
mRNA	LCP2	CCLE	pan-cancer	AAC	0.32	3e-08
mRNA	RNF220	CCLE	pan-cancer	AAC	0.26	3e-08
mRNA	AZU1	CCLE	pan-cancer	AAC	0.25	4e-08
mRNA	ADGRA2	CCLE	pan-cancer	AAC	0.28	6e-08
mRNA	ELANE	CCLE	pan-cancer	AAC	0.24	6e-08
mRNA	PECAM1	CCLE	pan-cancer	AAC	0.27	6e-08
mRNA	CD300A	CCLE	pan-cancer	AAC	0.27	7e-08
mRNA	PRAM1	CCLE	pan-cancer	AAC	0.25	7e-08

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