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RAF265

Synonyms

SourcesNames Used
CCLE, FIMM, CTRPv2RAF265
PharmacoGx RAF265

External IDs

DatabaseIdentifier
Smiles: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Inchikey: YABJJWZLRMPFSI-UHFFFAOYSA-N
Pubchem: 11656518

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to RAF265


Feature TypeStandardized
Nominal ANOVA
mRNA HIP1R CCLE pan-cancer AAC -0.17 0.0007
mRNA IRS2 CCLE pan-cancer AAC 0.18 0.0007
mRNA EXOSC9 CCLE pan-cancer AAC 0.18 0.0007
mRNA GRIN2C CCLE pan-cancer AAC -0.17 0.0007
mRNA PISD CCLE pan-cancer AAC 0.17 0.0007
mRNA RNASE2 CCLE pan-cancer AAC 0.17 0.0007
mRNA NTRK2 FIMM pan-cancer AAC 0.57 0.0007
mRNA SH2D5 CCLE pan-cancer AAC 0.19 0.0007
mRNA NUP54 CCLE pan-cancer AAC 0.17 0.0007
mRNA UBASH3B CCLE pan-cancer AAC 0.17 0.0007
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