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Panobinostat

Synonyms

SourcesNames Used
CCLE, FIMMPanobinostat
GRAYLBH589
CTRPv2LBH-589
PharmacoGx Panobinostat

External IDs

DatabaseIdentifier
Smiles: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO
Inchikey: FPOHNWQLNRZRFC-ZHACJKMWSA-N
Pubchem: 6918837

Annotated Targets

HDAC8, HDAC1, HDAC2, HDAC3, HDAC4, HDAC6, HDAC7, HDAC9, HDAC5, HDAC10

FDA Approval Status

Not Approved
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Top molecular features associated with response to Panobinostat


Feature TypeStandardized
Nominal ANOVA
mRNA CXCL12 CTRPv2 pan-cancer AAC -0.12 0.0004
mRNA ACACA CCLE pan-cancer AAC 0.14 0.0004
mRNA ACP1 CCLE pan-cancer AAC 0.15 0.0004
mRNA EPT1 CCLE pan-cancer AAC 0.15 0.0004
mRNA SREBF2 CCLE pan-cancer AAC 0.16 0.0004
mRNA RAB37 CCLE pan-cancer AAC 0.17 0.0004
mRNA KIAA1211 CTRPv2 pan-cancer AAC 0.13 0.0004
mRNA TTC39A CCLE pan-cancer AAC 0.16 0.0004
mRNA PRR12 CTRPv2 pan-cancer AAC 0.12 0.0004
mRNA SH3BGRL CTRPv2 pan-cancer AAC -0.14 0.0004
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