1. Home/
  2. Compounds/
  3. Irinotecan

Irinotecan

Synonyms

SourcesNames Used
CCLE, FIMMIrinotecan
gCSIirinotecan
GRAYCPT-11
PharmacoGx Irinotecan

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
Inchikey: UWKQSNNFCGGAFS-XIFFEERXSA-N
Pubchem: 60838

Annotated Targets

TOP1, TOP1MT

FDA Approval Status

Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to Irinotecan


Feature TypeStandardized
Nominal ANOVA
mRNA OR1D2 gCSI pan-cancer AAC -0.17 0.001
mRNA RAPGEF3 CCLE pan-cancer AAC -0.21 0.001
mRNA QRSL1 CCLE pan-cancer AAC 0.19 0.001
mRNA CD55 CCLE pan-cancer AAC -0.17 0.001
mRNA COL20A1 gCSI pan-cancer AAC -0.17 0.001
mRNA VMO1 CCLE pan-cancer AAC 0.16 0.001
mRNA GPR143 gCSI pan-cancer AAC -0.18 0.001
mRNA CHMP2A CCLE pan-cancer AAC -0.17 0.001
mRNA PPP3CA CCLE pan-cancer AAC -0.18 0.001
mRNA RNASE1 CCLE pan-cancer AAC -0.17 0.001
Download CSV