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Rapamycin

Synonyms

SourcesNames Used
GDSC1000, GRAYRapamycin
gCSIrapamycin
CTRPv2sirolimus
PharmacoGx Rapamycin

External IDs

DatabaseIdentifier
Smiles: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
Inchikey: QFJCIRLUMZQUOT-HPLJOQBZSA-N
Pubchem: 5284616

FDA Approval Status

Approved
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Top molecular features associated with response to Rapamycin


Feature TypeStandardized
Nominal ANOVA
mRNA SLC39A4 gCSI pan-cancer AAC -0.17 0.002
mRNA UCHL3 gCSI pan-cancer AAC 0.17 0.002
mRNA PEX5 CTRPv2 pan-cancer AAC 0.1 0.002
mRNA CRYBA1 GDSC1000 pan-cancer AAC 0.15 0.002
mRNA WWTR1 CTRPv2 pan-cancer AAC -0.13 0.002
mRNA MSANTD2 CTRPv2 pan-cancer AAC 0.1 0.002
mRNA PAWR gCSI pan-cancer AAC 0.19 0.002
mRNA STOML2 GDSC1000 pan-cancer AAC -0.15 0.002
mRNA ME2 gCSI pan-cancer AAC 0.2 0.002
mRNA PSMB9 GDSC1000 pan-cancer AAC 0.21 0.002
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