PharmacoDB

Sources

Names Used

Rapamycin

rapamycin

sirolimus

PharmacoGx

Rapamycin

Database	Identifier
Smiles:	CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
Inchikey:	QFJCIRLUMZQUOT-HPLJOQBZSA-N
Pubchem:	5284616

Database

Identifier

Smiles:

CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC

Inchikey:

QFJCIRLUMZQUOT-HPLJOQBZSA-N

Pubchem:

Top molecular features associated with response to Rapamycin

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IFNAR1	GDSC1000	pan-cancer	AAC	0.23	2e-05
mRNA	HLA-DQA2	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	HMCES	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	MYB	gCSI	pan-cancer	AAC	-0.31	2e-05
mRNA	C7orf72	gCSI	pan-cancer	AAC	0.27	2e-05
mRNA	ZMYND11	gCSI	pan-cancer	AAC	-0.26	2e-05
mRNA	ZCCHC2	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	ESYT3	gCSI	pan-cancer	AAC	-0.25	2e-05
mRNA	NEK9	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	SLC51A	gCSI	pan-cancer	AAC	-0.22	2e-05