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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA KRTAP11-1 gCSI pan-cancer AAC -0.2 7e-05
mRNA EIF3I gCSI pan-cancer AAC 0.2 7e-05
mRNA FASTK gCSI pan-cancer AAC -0.22 7e-05
mRNA TMEM198 GDSC1000 pan-cancer AAC -0.15 7e-05
mRNA FAM102A gCSI pan-cancer AAC -0.2 7e-05
mRNA KIAA1456 CTRPv2 pan-cancer AAC 0.13 7e-05
mRNA HIGD1B gCSI pan-cancer AAC 0.19 7e-05
mRNA OPRD1 gCSI pan-cancer AAC -0.23 7e-05
mRNA TMEM143 gCSI pan-cancer AAC -0.22 7e-05
mRNA SNRNP40 CTRPv2 pan-cancer AAC 0.12 7e-05
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