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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA RFX5 GDSC1000 pan-cancer AAC 0.17 5e-05
mRNA ZNF716 gCSI pan-cancer AAC -0.2 5e-05
mRNA CIB1 CTRPv2 pan-cancer AAC -0.13 5e-05
mRNA MTMR4 CTRPv2 pan-cancer AAC 0.13 5e-05
mRNA CELF3 gCSI pan-cancer AAC -0.22 5e-05
mRNA SENP6 CTRPv2 pan-cancer AAC 0.12 5e-05
mRNA OGFOD2 gCSI pan-cancer AAC -0.21 5e-05
mRNA HNRNPU gCSI pan-cancer AAC 0.2 5e-05
mRNA SNCB CTRPv2 pan-cancer AAC 0.12 5e-05
mRNA PCNX3 gCSI pan-cancer AAC -0.23 5e-05
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