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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA SMG5 gCSI pan-cancer AAC -0.21 4e-05
mRNA SPATA25 gCSI pan-cancer AAC -0.21 4e-05
mRNA EXT1 CTRPv2 pan-cancer AAC -0.14 4e-05
mRNA SLC22A17 GDSC1000 pan-cancer AAC -0.16 4e-05
mRNA RAB11FIP5 CTRPv2 pan-cancer AAC -0.14 4e-05
mRNA POFUT1 CTRPv2 pan-cancer AAC -0.13 4e-05
mRNA RP11-722G7.1 CTRPv2 pan-cancer AAC 0.13 4e-05
mRNA SCMH1 CTRPv2 pan-cancer AAC 0.12 4e-05
mRNA GRID2IP CTRPv2 pan-cancer AAC 0.12 4e-05
mRNA APAF1 CTRPv2 pan-cancer AAC 0.12 4e-05
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