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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA AATK-AS1 CTRPv2 pan-cancer AAC 0.15 4e-06
mRNA ABCB1 GDSC1000 pan-cancer AAC -0.16 4e-05
mRNA ABCC1 CTRPv2 pan-cancer AAC -0.16 3e-08
mRNA ABCC3 CTRPv2 pan-cancer AAC -0.15 5e-06
mRNA ABCE1 gCSI pan-cancer AAC 0.2 7e-05
mRNA ABHD12 CTRPv2 pan-cancer AAC -0.13 6e-05
mRNA ABHD16B gCSI pan-cancer AAC -0.25 1e-06
mRNA ABHD17B CTRPv2 pan-cancer AAC 0.18 5e-09
mRNA ABLIM3 CTRPv2 pan-cancer AAC -0.13 4e-05
mRNA ABRACL CTRPv2 pan-cancer AAC 0.14 2e-05
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