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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA ACTN4 CTRPv2 pan-cancer AAC -0.15 1e-06
mRNA ACTR2 gCSI pan-cancer AAC 0.21 6e-05
mRNA ACVR2B CTRPv2 pan-cancer AAC 0.17 7e-07
mRNA ADAD1 gCSI pan-cancer AAC -0.19 7e-05
mRNA ADAM9 CTRPv2 pan-cancer AAC -0.15 2e-05
mRNA ADAT2 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA ADCK5 gCSI pan-cancer AAC -0.25 1e-06
mRNA ADCY2 gCSI pan-cancer AAC -0.23 1e-05
mRNA ADGRG1 gCSI pan-cancer AAC -0.37 5e-09
mRNA ADGRG7 gCSI pan-cancer AAC -0.23 7e-06
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