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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA MARVELD2 gCSI pan-cancer AAC -0.34 2e-06
mRNA HDAC11 gCSI pan-cancer AAC -0.34 1e-08
mRNA CLDN3 gCSI pan-cancer AAC -0.34 2e-07
mRNA PRR15L gCSI pan-cancer AAC -0.33 5e-09
mRNA C2CD4A gCSI pan-cancer AAC -0.33 1e-09
mRNA SH3BGRL2 gCSI pan-cancer AAC -0.33 1e-07
mRNA RAB19 gCSI pan-cancer AAC -0.33 7e-08
mRNA FAAH2 gCSI pan-cancer AAC -0.33 7e-09
mRNA GPR37L1 gCSI pan-cancer AAC -0.33 3e-09
mRNA DSP gCSI pan-cancer AAC -0.32 1e-05
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