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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA PRPF4B GDSC1000 pan-cancer AAC 0.15 8e-05
mRNA PGAP1 CTRPv2 pan-cancer AAC 0.12 8e-05
mRNA USP21 gCSI pan-cancer AAC -0.2 8e-05
mRNA RPN2 gCSI pan-cancer AAC -0.2 8e-05
mRNA WNK2 CTRPv2 pan-cancer AAC 0.12 8e-05
mRNA LYPD4 gCSI pan-cancer AAC -0.2 8e-05
mRNA BRI3 GDSC1000 pan-cancer AAC -0.14 8e-05
mRNA INO80B-WBP1 gCSI pan-cancer AAC -0.19 8e-05
mRNA DNHD1 gCSI pan-cancer AAC -0.22 8e-05
mRNA SPINK5 gCSI pan-cancer AAC -0.21 8e-05
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