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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA NCBP3 gCSI pan-cancer AAC 0.21 6e-05
mRNA OVOL2 gCSI pan-cancer AAC -0.25 6e-05
mRNA NFATC3 CTRPv2 pan-cancer AAC 0.16 6e-05
mRNA TMEM175 gCSI pan-cancer AAC -0.2 6e-05
mRNA GTSE1 CTRPv2 pan-cancer AAC 0.12 6e-05
mRNA FBXO41 CTRPv2 pan-cancer AAC 0.15 6e-05
mRNA MAPT CTRPv2 pan-cancer AAC 0.13 6e-05
mRNA HDDC2 gCSI pan-cancer AAC 0.21 6e-05
mRNA ABHD12 CTRPv2 pan-cancer AAC -0.13 6e-05
mRNA TLDC1 CTRPv2 pan-cancer AAC -0.13 6e-05
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