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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA DENND6A CTRPv2 pan-cancer AAC 0.18 1e-09
mRNA CD63 CTRPv2 pan-cancer AAC -0.22 1e-09
mRNA PARP1 CTRPv2 pan-cancer AAC 0.2 2e-09
mRNA C1orf210 gCSI pan-cancer AAC -0.37 2e-09
mRNA MAPK3 gCSI pan-cancer AAC -0.3 2e-09
mRNA SEPT5 CTRPv2 pan-cancer AAC 0.19 2e-09
mRNA STARD10 gCSI pan-cancer AAC -0.36 2e-09
mRNA RFXAP CTRPv2 pan-cancer AAC 0.21 2e-09
mRNA CEACAM16 gCSI pan-cancer AAC -0.3 2e-09
mRNA RPL3 CTRPv2 pan-cancer AAC 0.22 2e-09
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