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Doxorubicin

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMDoxorubicin
gCSI, CTRPv2doxorubicin
PharmacoGx Doxorubicin

External IDs

DatabaseIdentifier
Smiles: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
Inchikey: MWWSFMDVAYGXBV-FGBJBKNOSA-N
Pubchem: 32874

Annotated Targets

TOP2A

FDA Approval Status

Approved
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Top molecular features associated with response to Doxorubicin


Feature TypeStandardized
Nominal ANOVA
mRNA LDLRAD1 gCSI pan-cancer AAC -0.28 1e-08
mRNA SDR42E1 gCSI pan-cancer AAC -0.29 1e-08
mRNA HAUS6 gCSI pan-cancer AAC 0.28 1e-08
mRNA YIPF5 CTRPv2 pan-cancer AAC -0.2 1e-08
mRNA CDCA7 CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA SCO1 gCSI pan-cancer AAC 0.29 1e-08
mRNA ZNF852 CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA GADD45G gCSI pan-cancer AAC -0.31 1e-08
mRNA FAM209A CTRPv2 pan-cancer AAC -0.18 1e-08
mRNA TOP2B CTRPv2 pan-cancer AAC 0.19 1e-08
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