PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MYB	gCSI	pan-cancer	AAC	-0.24	0.002
mRNA	ABI2	gCSI	pan-cancer	AAC	-0.24	0.0002
mRNA	CORO7	gCSI	pan-cancer	AAC	-0.24	0.002
mRNA	SCG2	gCSI	pan-cancer	AAC	-0.24	0.0003
mRNA	GFI1	gCSI	pan-cancer	AAC	-0.24	0.0004
mRNA	ZNF697	gCSI	pan-cancer	AAC	-0.23	0.004
mRNA	TAAR1	gCSI	pan-cancer	AAC	-0.23	7e-05
mRNA	SMPD3	gCSI	pan-cancer	AAC	-0.23	8e-05
mRNA	ZNF175	gCSI	pan-cancer	AAC	-0.23	7e-05
mRNA	ACOT11	gCSI	pan-cancer	AAC	-0.23	0.0008