PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRKCQ	CTRPv2	pan-cancer	AAC	-0.17	1e-05
mRNA	TTC7B	CTRPv2	pan-cancer	AAC	-0.16	1e-05
mRNA	MKL1	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	GPR3	CTRPv2	pan-cancer	AAC	-0.17	2e-05
mRNA	IRF8	CTRPv2	pan-cancer	AAC	0.17	2e-05
mRNA	RBM7	CTRPv2	pan-cancer	AAC	-0.16	2e-05
mRNA	CR1L	CTRPv2	pan-cancer	AAC	-0.15	2e-05
mRNA	RCC1L	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	LIME1	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	STAT5A	CTRPv2	pan-cancer	AAC	-0.17	2e-05