PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GPR50	FIMM	pan-cancer	AAC	-0.47	0.006
mRNA	NCKAP1	GDSC1000	pan-cancer	AAC	-0.45	3e-12
mRNA	DYX1C1	gCSI	pan-cancer	AAC	-0.3	1e-05
mRNA	CNKSR3	gCSI	pan-cancer	AAC	-0.28	0.0001
mRNA	NTRK1	gCSI	pan-cancer	AAC	-0.28	9e-06
mRNA	USP18	gCSI	pan-cancer	AAC	-0.28	1e-05
mRNA	JADE3	gCSI	pan-cancer	AAC	-0.28	5e-06
mRNA	CD300A	gCSI	pan-cancer	AAC	-0.27	1e-05
mRNA	ZNF112	gCSI	pan-cancer	AAC	-0.27	0.002
mRNA	LCP2	gCSI	pan-cancer	AAC	-0.27	0.0004