PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	APC	FIMM	pan-cancer	AAC	0.62	0.002
mRNA	KIAA1033	FIMM	pan-cancer	AAC	0.62	0.0006
mRNA	ERBB4	FIMM	pan-cancer	AAC	0.62	0.0008
mRNA	CLDN3	FIMM	pan-cancer	AAC	0.63	0.002
mRNA	SEMA3C	FIMM	pan-cancer	AAC	0.63	0.002
mRNA	USP15	FIMM	pan-cancer	AAC	0.68	0.001
mRNA	SESN1	FIMM	pan-cancer	AAC	0.68	0.003
mRNA	JAK2	FIMM	pan-cancer	AAC	0.7	4e-05
mRNA	PPIP5K2	FIMM	pan-cancer	AAC	0.7	0.002
mRNA	RHBDF1	FIMM	pan-cancer	AAC	0.84	0.003