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GDC-0941

Synonyms

SourcesNames Used
GDSC1000GDC0941
gCSIgdc0941
FIMMPictilisib
CTRPv2GDC-0941
PharmacoGx GDC-0941

External IDs

DatabaseIdentifier
Smiles: CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey: LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem: 17755052

Annotated Targets

PIK3CA, PIK3CB, PIK3CD, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to GDC-0941


Feature TypeStandardized
Nominal ANOVA
mRNA CXCR5 gCSI pan-cancer AAC 0.25 4e-05
mRNA RNF122 CTRPv2 pan-cancer AAC 0.16 4e-05
mRNA JAK2 FIMM pan-cancer AAC 0.7 4e-05
mRNA TP53INP1 gCSI pan-cancer AAC 0.27 4e-05
mRNA ZCCHC2 CTRPv2 pan-cancer AAC 0.15 4e-05
mRNA UROD CTRPv2 pan-cancer AAC -0.15 4e-05
mRNA STPG1 CTRPv2 pan-cancer AAC -0.15 4e-05
mRNA TSEN15 GDSC1000 pan-cancer AAC -0.14 4e-05
mRNA CT55 CTRPv2 pan-cancer AAC -0.15 4e-05
mRNA STAM CTRPv2 pan-cancer AAC -0.15 4e-05
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