PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HEPACAM2	GDSC1000	pan-cancer	AAC	-0.095	0.006
mRNA	DCHS1	gCSI	pan-cancer	AAC	-0.2	0.006
mRNA	RRP7A	CTRPv2	pan-cancer	AAC	0.1	0.006
mRNA	ETV5	CTRPv2	pan-cancer	AAC	-0.11	0.006
mRNA	TBK1	FIMM	pan-cancer	AAC	0.47	0.006
mRNA	QARS	gCSI	pan-cancer	AAC	0.19	0.006
mRNA	KIFC3	CTRPv2	pan-cancer	AAC	-0.11	0.006
mRNA	COMTD1	CTRPv2	pan-cancer	AAC	0.11	0.006
mRNA	ZSCAN9	CTRPv2	pan-cancer	AAC	-0.1	0.006
mRNA	HNRNPM	CTRPv2	pan-cancer	AAC	0.1	0.006